Depends on the location. I use muscle creams or Biofreeze. If it's in my thigh, butt or low back I will use a rolling pin. Massage works well too. Often times I just resort to my heating pad and/or a hot shower. I hope this helps.

Try getting a foam roller. You can use a rolling pin, but it is painful. I use one almost everyday, you just place your leg or lay on it for your back and roll the muscle back and forth and or side to side. That and pain med rubs are the only thing that works for me.

Pedro....As others stated....massage; stretching & muscle relaxers......A physical therapist use to massage in hot water so since I had a hot tub I let the jets massage these knots out....My tub is a "Soft Tub" and it came with all different types of therapy gadgets. One was a short hose that hooked directly to a jet and came out in a force. Was called "soft tissue treatment"....Same as pt called it. Just hold it over the spots for a little while....

I will lean up against the corner of the door jam and work it out. Depending on where it is. It works for me. Then I will ice it.

I receive lidocaine injections in my neck and upper/lower back. My neurologist started these injections although, they can also be given by an orthopedist. I have found, if I take my muscle relaxer, Paraflex, at least 3 times/day, the muscles are more relaxed and spasms less frequent.