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Real members of MyFibroTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.

Advice Please? Can Anyone Give Me Thier Experience Of Duloxetine (Cymbalta)?

A MyFibroTeam Member asked a question 💭
Plymouth, UK

I have been weaned off gabapentin and started my new prescription of duloxetine today. I was looking forward to this (strangely) as it meant bringing my total of 23 tablets down to two/day. The recommendation from the consultant was positive and I even found some research to support it's use with Fibro (couldn't tell you where tho). Got to be good right? Well I took my first dose this morning and OMG! What a horror - vomiting - (well intense dry heaving actually as I can't eat at the moment)… read more

May 9, 2016
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A MyFibroTeam Member

I have been taking Cymbalta for abt. 8 yrs. Please keep in mind that Any New medicine can/will take a few for your body to adjust. I know you need to titrate UP to 60mg (or more) yes I went through a lot of adjustment, but I hate to run out - cuz I get "body shocks" with every step I take. I am fairly certain that you experienced "A Serotonin Overdose" they can also manifest as a panic attack!! Please follow the instructions from your Doctor. I am willing to help you with anything else, or just listen! Good luck and have a pain free day!!

May 10, 2016
A MyFibroTeam Member

I take my Cymbalta at night. 90 mg. I take it with Lyrica, and the combination works well for me. Check with your doctor or pharmacist (Chemist) about the timing of the pills.

May 10, 2016
A MyFibroTeam Member

For years now I've been taking 1200mg 3 times a day of Neurontin and 60mg in the morning and 60mg at night of Cymbalta. It helps to a certain degree but not enough

May 9, 2016
A MyFibroTeam Member

I was on
Cymbalta for three years. It did help with pain but I gained a ton of weight. Its very difficult to get off of once on it because the body experiences pain like no other I have ever felt throughout my body. So I started a new prescription called Fetzima and I am alert, losing my weight and it helped with my depression. However It did not help my anxiety and I have to get off of Fetzima because I have had allergy reactions such as intense itching and sometimes red swollen skin on my legs and hands and feet. . So in 4 days I will be off Fetzima. I was also very alert and able to focus. I hope they find something that works with out gaining weight.

May 9, 2016
A MyFibroTeam Member

I have no problem with the Gabapentin. It helps me with my legs and arms. Cymbalta made me sick. Everyone is different though. Hopefully after a week you can get over the side effects your having. If not then go back to what worked until you find something else. Take Care of yourself.

June 25, 2016

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