I was having a lot a trouble with RLS until I tried a patch called Neupro. It works for 24 hours.

Have ur iron level checked. My dr told me that rls gets worse when ur iron is low. He did a blood test n my iron was very low... have iron deficiency anemia. He sent me for iron infusion therapy n I havent had rls for 5 mos.

I would not personally recommend nortriptyline as antidepressants can worsen RLS because they mess with dopamine. But a few people say they help. I would suggest Dopamine drugs like Pramiprexol, gabapentin and if these fail codeine or tramadol. All can have harsh side effects depending on the person, while some do really well. Dopamine drugs are usally the first choice as these have the most evidence. I personally use 30mg of codeine in the evening and 30mg before bed. I also use CBD Hemp oil which has been very helpful with little side effects...basically its a legal form of cannabis you can get from health stores it has zero psychoactive properties and does not get you high.

I take natural supplements. Since starting them, my RLS is gone. My 31 y/o daughter had the same results for her RLS. I would love to give you more info. If you are interested, let me know.

I had a sleep study done and discovered I have Sleep Apnea and Restless Leg. Since I've been using my CPAP machine for Sleep Apnea, no more Restless Leg!