I am the opposite. I require higher doses of most everything.

I am incredibly sensitive to medication as well. I had a bad reaction to the lyrica and gabapentin. With the help of a functional doc, I switched to more natural remedies. GABA is the natural form or gabapentin and it has been much more tolerable for me. I couldn't take the antidepressants either. I am much like your parents though and don't really trust western medicine.

Hello, I,m very sensitive to drugs,cannot take any anti inflamitive medication,also certain foods I,m sensitive too.It's been a rollercoaster trying to get on the correct medication which helps,weaning on pills,weaning off pills because of all the side affects,having to take things very slowly to see how I react to them I,m now takeing pregabalin which at the moment seems to be the only drug that I feel has helped but I have been increasing it very very slowly,I've done it my way,listening to my body and hopefully this is the meds for me.Morning's are still not good,and this cold weather really doesn,t help but I,m staying positive.But yes I definitely think people with this condition are more sensitive to a lot of things !!!!x

No, I cannot take any antidepressants, they wig me out, actually make me feel depressed.

Yes, I am incredibly sensitive to any medication. I always start off with the smallest dose and break it in quarters if possible. I even pull apart my Lyrica and scoop up a small portion in the capsule, put the powder on my tongue, yucky, it tastes so awful, but it is working for me this way. :)