Duloxetine is supposed to be taken at night to help you sleep. Maybe try it when you get home from work

Thank you all so much, I've tried taking them at night for the past few days and it seems to help me in the mornings, however the meds don't help at all yet 😩😩

I have had good results taking Duloxetine (90mg.) first thing in the morning with breakfast. I've been on this dosage for a year. I have my coffee & I'm good to go. Gabepentin is another med I also take with it-no problems. For sleeping at night, I take 5mg. Melatonin which is a natural solution to get good sleep.

I take meds both morning and night. About a half hour before bed I take two tramadol and that seems to help me sleep. How long does it take before your meds kick in? Could you take them before you leave work? How long have you been on this med? Sometimes it takes about 2 weeks for your body to get adjusted to new medications. Also talk to your pharmacist and see if s/he can offer any help.

I've found making sure I take my meds at the same time everyday works best. I have nerve damage in my back as well as FM and take an extended release med and have a pain med also. I take my extended 1 hr before I take amtryptiline to help me sleep and the night pain. I am up to 50mg. I hope this helps.