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Real members of MyFibroTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.

Have You Found Depression To Become More Severe After Coming Off Medications Like Lyrica Or Cymbalta?

A MyFibroTeam Member asked a question 💭
Downingtown, PA

I have given @Cymbalta a shot for roughly 2 months, but due to some side effects my medical team all agreed that this was not a wise move to continue use. I have been off the medication for a few weeks now (weened off properly), but I am noticing depression has been creeping up on my heavily, but it is seriously uncommon for me to have bouts like this.

Has anyone had similar issue with this? I am fairly surprised to see how intense some of it has been feeling, and really hope this passes… read more

August 28, 2017 (edited)
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A MyFibroTeam Member

I'm getting ready to come off Lyrica going to Gabapentin. I came off of Lyrica once on my own cold turkey and definitely had worsened depression

August 28, 2017
A MyFibroTeam Member

@A MyFibroTeam Member My doctor wrote new scripts to lower the dosage to start the step down, and then we went to breaking the lowest dosage capsules down and only take a small bead count from the pill for a few weeks

August 29, 2017
A MyFibroTeam Member

How did you wean? If you did not wean properly you could be having withdrawals

August 29, 2017
A MyFibroTeam Member

I know when I've come off meds that have withdrawal my depression is. As far as the ones you've listed I haven't tried.

August 28, 2017
A MyFibroTeam Member

I did not do well with either Cymbalta or Lyrica. Lyrica made me want to die. Check with your doctor for a better choice. Zoloft does not bother me, it makes me feel more energetic as well.

August 31, 2017

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