Yes, one of the first symptoms of Fibro that I had was hyper-reflex. I also have tremors, muscle twitching and spasms all over my body. The worst ones occur at the bottom of my rib cage. For 2 years the muscle spasms would have me on the floor withering for 20 minutes or more, leaving me exhausted. Some nights I would have multiple episodes, greatly affecting my sleep. One of my specialists finally put me on Mirapex/pramipexole (controls muscle spasms and twitching) which gave me great relief. I still get muscle spasms, but the medication makes each occurrence short-lived. Seems like a miracle drug to me! :-)

I have had the muscle cramps, twitches and large groups of muscle fasiculations for over 5 years. Neurologist said hyper reflexive in my right knee. It seems that these symptoms, if not accompanied by other more definitive ones, do not pose any kind of threat. Many folks without any kind of autoimmune condition can have these fasiculations - called Benign Fasiculation Syndrome. There is a big difference between hyperreflexia which is a condition of the autonomic nervous system and having a reflex considered over "reactive".

I do take Magnesium and it seems to have helped both the severity and frequency of all that, including heart palpitations.

Always, always check with your doctor before starting any kind of supplements. You might want to check with the pharmacist, as well. They are a wealth of knowledge about interactions, etc.

Hi There! I have had fibro for three years and the muscle twitching has been on going since October 2018 as well. Now by muscle twitching i mean fasciculations. (Not full body movements like jerking, people tend to get those confused). So yes, I experience them everywhere, including the stomach, arms, hands, back, butt, eyes, neck, and legs and feet. Sometimes I have hotspots, where it twitches in one spot for days and leaves the area in pain and weak. I went to a neuromuscular neurologist in December, because i made the mistake of googling it and scared myself into thinking I had a dreadful disease. I had a thorough exam, nerve studies, EMG, and MRI. All came back negative. Some days the twitching is minimal, sometimes its constant all over. Now just know that hyper reflexia is common in fibromyalgia because our nerves are constantly in a fight or flight mode. True hyper reflexia would literally cause your limb to fly off the table once its been hit. My advice, meet with the neuro, request the nerves studies, ask for vitamin deficiencies to be tested. Mine are low and since I've been supplementing the last three months I have seen a decrease in the twitching, but not eliminated. There is a high probability that you are just fine, but it will bring you peace of mind. Another point, muscle fasciculations are a symptom of fibro. And remember not everyone's experience is the same. Best Wishes.