Savella was really beginning to help my pain symptoms when I developed intolerable side effects. I was very disappointed. I was told that Savella has a history of causing significant side effects.

Hi Kitty, I took 5 different antidepressants over the course of a year to find something effective and Savella was the one for me. It affects the norepinepherine neurotransmitter twice as much as any other, which not only helps with pain but can also give you some energy. You're also not as likely to gain weight while taking it. It has helped me a lot over the past 6 years and I plan to stay on it

Hi Kitty. I was on duloxetine 60mg for a few month, but found i was too drousy and brain fog was worse. Do you feel the same ? I do also suffer with M.E. chronic fatigue also. How are you ? Best wishes from pauliine c xx

Yes, since 1985. I'm on duloxetine 60 mg, 2 per day, gabapentin 400 bedtime, bupropion 450 mg daily, and more.

Hi There. I take Duloxetine 30mg which is a similar type of drug. Also take Pregabalin, Tramadol and Sumatriptan for my headaches. All must help i guess but am having a long bad spell of pain and anxiety. Worse than ever. Suffefed for years !!. Have you suffered long ? and how are you today ? 🌼🌻🌺🤗🌈