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Real members of MyFibroTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.

Has Anyone Tried Low Dose Naltrexone?

A MyFibroTeam Member asked a question 💭
Vancouver, BC

My doctor is recommending a trial of this, and I am uncertain, as I have had either bad side effects, or poor results from most medications.

May 20, 2023
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A MyFibroTeam Member

I'm looking into trying this as well. My therapist uses it and said it has changed her life. She doesn't had fibro but had chronic pain disorder of some sort. She was the 2nd person to recommend it to me. I have hypermobility, migraines, fatigue, and Connective Tissue Disorder (undefined but likely seronegative RA)... please keep us updated!

May 20, 2023
A MyFibroTeam Member

I am currently on this along with Lyrica and amatriptalin and it's helped quite a bit. I take six at night so far

May 20, 2023
A MyFibroTeam Member

Thank you Victoria3. I am aware of what the medication is, however, just wondering other's experiences of trying the low dose option for pain control in fibro. It is an off label use.

May 22, 2023
A MyFibroTeam Member

Naltrexone is used to help narcotic dependents who have stopped taking narcotics to stay drug-free and to help alcoholics. The medicine is not a cure for addiction.

Naltrexone works by blocking the effects of narcotics. You cannot "combine" naltrexone or alternate it with another pain medication!

Naltrexone will cause withdrawal symptoms in people who are physically dependent on narcotics. Naltrexone treatment is started after you are no longer dependent on narcotics. This depends on which narcotic you took, how much, and how long you took it. Before starting naltrexone tell your doctor if you are having withdrawal symptoms.

This medicine is available only with a doctor's prescription.

Note: if you take low-dose naltrexone, your other pain-relieving narcotic medications will not work! Many persons with fibromyalgia or other painful conditions do take a narcotic medication on an as-needed basis, such as during flares. Naltrexone blocks the effects of narcotic medications.

May 22, 2023

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